The United States Government’s (USG) Global Food Security Strategy (GFSS) is an integrated whole-of-government approach that aims to end global hunger, poverty, and malnutrition through the Feed the Future initiative. Launched in 2010 across Africa, Asia, Latin America, and the Caribbean, Feed the Future aims to stimulate agriculture-led growth, resilience, and nutrition in countries with significant needs and opportunities for improvement. Through partnerships that invest in agriculture, build resilience, and improve nutrition, the USG has provided the basic dignity of food to millions of families worldwide. This initiative has delivered impressive results, including an estimated 23.4 million people lifted to above the poverty line, 3.4 million children no longer stunted, and an estimated 5.2 million families overcoming hunger. Additionally, Feed the Future has unlocked $3.5 billion in financing for food security (2011–2019), generated $13.7 billion in agricultural sales, and developed and deployed over 1,000 innovations.